Frequently Asked Questions

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Omeprazole FAQs

How does Omeprazole treat frequent heartburn?

Omeprazole is a Proton Pump Inhibitor (PPI) that provides long-lasting relief† of frequent heartburn. It works in the body by blocking the pumps that produce stomach acid, preventing acid production right at the source. This means the acid won't flow up into your esophagus and cause uncomfortable symptoms. So, by taking Omeprazole, you can prevent heartburn from happening in the first place.

Are Omeprazole ingredients comparable to Prilosec OTC?

Store branded Omeprazole and Prilosec OTC are both FDA-approved to treat frequent heartburn. Since both products contain the same active ingredient, Omeprazole, you can trust that the store branded version will be just as effective.

How quickly does Omeprazole work?

Omeprazole is a 14-day course treatment. While some people may start to feel relief within 24 hours, it usually takes between 1 to 4 days for the medicine to take full effect. It’s important to take the full course of treatment even if you start to feel better before the 14 days are up.

How does Omeprazole compare to other heartburn treatments?

Omeprazole is a Proton Pump Inhibitor (PPI), and its main function is to decrease the amount of acid produced in your stomach. This medication is recommended for individuals who experience frequent heartburn symptoms that occur 2 or more days a week.

There are 3 types of medications that can help reduce stomach acid: antacids, histamine H2-receptor antagonists (H2 blockers) and PPIs. Although they all work to reduce acid, each medication type works in slightly different ways. Antacids work by neutralizing stomach acid to provide immediate but short-term relief, typically lasting for up to 2 hours. H2 blockers work by blocking a type of histamine receptor in the stomach that stimulates acid production. These medications can help decrease acid production for approximately 6-12 hours. PPIs like Omeprazole are taken for a duration of 14 days and work by blocking the pumps that produce stomach acid, preventing acid production right at the source. They may take 1-4 days for full effect, but relief lasts for 24 hours. This longer-lasting relief can make a significant difference for those who suffer from frequent heartburn.

Who should take Omeprazole?

Omeprazole is safe and effective for individuals who suffer from frequent heartburn symptoms that occur 2 or more days per week. If you are pregnant or breast-feeding, ask a health professional before using Omeprazole.

How many times a day will I have to take Omeprazole?

Take Omeprazole once a day (every 24 hours) for 14 days. You may repeat a 14-day course of treatment every 4 months. If you need to take this 14-day regimen more than 3 times a year (every 4 months), discontinue use until you have spoken with your doctor. This is necessary to ensure that you are not missing any underlying health issues, such as GERD. Omeprazole should not be taken for more than 14 days or more frequently than every 4 months, unless directed by a doctor.

Should I take Omeprazole before eating?

To treat frequent heartburn for up to 24 hours†, it is recommended you take 1 pill for 14 consecutive days with a glass of water before eating in the morning. However, do not take it more than 3 times a year (every 4 months) unless directed by a doctor.

Can I use Omeprazole if I’m pregnant?

If you are pregnant or breast-feeding, ask a health professional before using Omeprazole.

What are the side effects associated with taking Omeprazole?

Please see the Drug Facts Label on the package for more information.

Heartburn FAQs

What is heartburn?

Heartburn is the uncomfortable burning sensation in your chest and throat when stomach acid flows up into the esophagus – the tube that connects your throat to your stomach. If you're feeling a burning sensation in your chest 2 or more times per week, than you may have frequent heartburn. When taken as directed, Omeprazole provides long-lasting, 24-hour relief† of frequent heartburn symptoms.

What is acid reflux?

Acid reflux is a common condition where stomach acid and digested food flow back into your esophagus. This can happen when the esophageal sphincter (LES) muscle at the bottom of your esophagus doesn’t close properly or is weakened, resulting in a burning sensation in the chest (known as heartburn).

What is gastroesophageal reflux disease (GERD)?

Heartburn that occurs frequently and interferes with your routine is considered gastroesophageal reflux disease (GERD). GERD is a chronic condition that occurs when stomach acid repeatedly flows back into the esophagus, causing irritation and inflammation. GERD can cause symptoms such as heartburn, chest pain, difficulty swallowing and regurgitation of food or sour liquid.§ GERD can also lead to complications such as esophageal ulcers and bleeding in the lining of the esophagus.‡ Most people can manage GERD with lifestyle changes and medications. In more severe cases, medication or even surgery may be necessary to ease symptoms. Omeprazole is not indicated for the treatment of GERD. Talk to your doctor if you experience these symptoms on a regular basis.

What causes heartburn symptoms?

Fatty and fried foods, spicy foods, as well as caffeine, alcohol and tobacco can trigger heartburn symptoms. Other factors that can contribute to heartburn include stress, obesity, pregnancy and certain medications. Understanding the causes of heartburn can help you take steps to prevent or alleviate your symptoms.

What are some other ways to combat frequent heartburn?

In addition to taking Omeprazole, try avoiding foods that may make your heartburn symptoms worse. Fatty and fried foods, spicy foods, as well as caffeine, alcohol and tobacco can all contribute to the painful, burning sensation heartburn causes. Avoid clothes that are too tight-fitting, lying down after a meal, smoking, and if you are overweight, make healthy lifestyle choices that can help you to lose weight.

Why do I experience more heartburn at bedtime?

When you lie down, stomach acid can flow back up into your esophagus, leading to heartburn. This also makes it easier for the acid to irritate the lining of your esophagus. To help prevent nighttime heartburn, avoid eating large meals or drinking a lot of fluids before bedtime. Elevate the head of your bed and avoid lying down for at least 3 hours after eating.

What foods are known to trigger heartburn?

Certain types of food can cause heartburn symptoms to flare up. These are called heartburn "triggers." Foods and beverages that can trigger or worsen heartburn include rich, spicy, fatty and fried foods, chocolate, caffeine, alcohol and certain fruits and vegetables.

† Not for immediate relief. May take 1-4 days for full effect.

‡ Definition & Facts for GER & GERD. National Institute of Diabetes and Digestive and Kidney Diseases. Reviewed July 2020. Accessed May 11, 2023.

§ Symptoms & Causes of GER & GERD. National Institute of Diabetes and Digestive and Kidney Diseases. Reviewed July 2020. Accessed May 11, 2023.